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Adipose Angptl8 Controls Glucose and Energy Metabolism and its Suppression in Mice Improves Diet Induced Obesity and Inflammation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/dmrr.2919openalex-extracted
ANGPTL8 (betatrophin) role in diabetes and metabolic diseases
inferredcites →https://doi.org/10.1002/dmrr.3643openalex-extracted
Plasma insulin is required for the increase in plasma angiopoietin‐like protein 8 in response to nutrient ingestion
inferredcites →https://doi.org/10.1002/dvg.20665openalex-extracted
Tamoxifen‐inducible Cre‐mediated recombination in adipocytes
inferredcites →https://doi.org/10.1002/j.1550-8528.1997.tb00584.xopenalex-extracted
The Thermic Effect of Food and Obesity: A Critical Review
inferredcites →https://doi.org/10.1002/oby.20811openalex-extracted
Variations in body weight, food intake and body composition after long-term high-fat diet feeding in C57BL/6J mice
inferredcites →https://doi.org/10.1002/oby.22674openalex-extracted
Adipose Tissue Macrophage Phenotypes and Characteristics: The Key to Insulin Resistance in Obesity and Metabolic Disorders
inferredcites →https://doi.org/10.1006/bbrc.2001.4217openalex-extracted
Chromosomal Localization, Expression Pattern, and Promoter Analysis of the Mouse Gene Encoding Adipocyte-Specific Secretory Protein Acrp30
inferredcites →https://doi.org/10.1007/978-3-319-48382-5_9openalex-extracted
The Pathogenesis of Obesity-Associated Adipose Tissue Inflammation
inferredcites →https://doi.org/10.1007/bf00280883openalex-extracted
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
inferredcites →https://doi.org/10.1007/s00125-018-4579-1openalex-extracted
Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents
inferredcites →https://doi.org/10.1007/s10557-019-06924-7openalex-extracted
Increased Circulating Angiopoietin-Like Protein 8 Levels Are Associated with Thoracic Aortic Dissection and Higher Inflammatory Conditions
inferredcites →https://doi.org/10.1016/0021-9150(78)90155-7openalex-extracted
Lipoprotein-lipase activity in human skeletal muscle and adipose tissue in the fasting and the fed states
inferredcites →https://doi.org/10.1016/0026-0495(88)90178-3openalex-extracted
Regulation of lipoprotein lipase in different rat tissues
inferredcites →https://doi.org/10.1016/b978-0-12-411619-1.00006-9openalex-extracted
Quantifying Size and Number of Adipocytes in Adipose Tissue
inferredcites →https://doi.org/10.1016/j.alcohol.2015.03.005openalex-extracted
Dissociation between diurnal cycles in locomotor activity, feeding behavior and hepatic PERIOD2 expression in chronic alcohol-fed mice
inferredcites →https://doi.org/10.1016/j.bbalip.2024.159461openalex-extracted
Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling
inferredcites →https://doi.org/10.1016/j.bbrc.2012.07.038openalex-extracted
Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels
inferredcites →https://doi.org/10.1016/j.cca.2007.01.026openalex-extracted
Adiponectin as an anti-inflammatory factor
inferredcites →https://doi.org/10.1016/j.cell.2013.12.012openalex-extracted
What We Talk About When We Talk About Fat
inferredcites →https://doi.org/10.1016/j.celrep.2016.02.076openalex-extracted
α/β-Hydrolase Domain 6 Deletion Induces Adipose Browning and Prevents Obesity and Type 2 Diabetes
inferredcites →https://doi.org/10.1016/j.chemphyslip.2017.05.002openalex-extracted
Angiopoietin-like 8 (Angptl8) controls adipocyte lipolysis and phospholipid composition
inferredcites →https://doi.org/10.1016/j.cyto.2016.10.011openalex-extracted
Leptin in inflammation and autoimmunity
inferredcites →https://doi.org/10.1016/j.gene.2020.144707openalex-extracted
ANGPTL8 enhances insulin sensitivity by directly activating insulin-mediated AKT phosphorylation
inferredcites →https://doi.org/10.1016/j.jare.2022.08.006openalex-extracted
ANGPTL8 accelerates liver fibrosis mediated by HFD-induced inflammatory activity via LILRB2/ERK signaling pathways
inferredcites →https://doi.org/10.1016/j.jlr.2021.100150openalex-extracted
Role and mechanism of the action of angiopoietin-like protein ANGPTL4 in plasma lipid metabolism
inferredcites →https://doi.org/10.1016/j.molmet.2017.06.014openalex-extracted
ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase
inferredcites →https://doi.org/10.1016/j.plipres.2020.101067openalex-extracted
The multi-faces of Angptl8 in health and disease: Novel functions beyond lipoprotein lipase modulation
inferredcites →https://doi.org/10.1016/j.plipres.2021.101140openalex-extracted
An updated ANGPTL3-4-8 model as a mechanism of triglyceride partitioning between fat and oxidative tissues
inferredcites →https://doi.org/10.1016/j.trsl.2016.06.012openalex-extracted
Angiopoietin-like protein 8 (ANGPTL8) in pregnancy: a brown adipose tissue–derived endocrine factor with a potential role in fetal growth
inferredcites →https://doi.org/10.1038/ncb3217openalex-extracted
Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation
inferredcites →https://doi.org/10.1038/ng814openalex-extracted
Angptl3 regulates lipid metabolism in mice
inferredcites →https://doi.org/10.1038/s41467-017-02355-wopenalex-extracted
ANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ
inferredcites →https://doi.org/10.1038/s41467-019-11513-1openalex-extracted
Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
inferredcites →https://doi.org/10.1038/s41467-023-40183-3openalex-extracted
LILRB2/PirB mediates macrophage recruitment in fibrogenesis of nonalcoholic steatohepatitis
inferredcites →https://doi.org/10.1038/s42255-019-0041-zopenalex-extracted
Metabolic Messengers: adiponectin
inferredcites →https://doi.org/10.1038/srep10949openalex-extracted
Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance
inferredcites →https://doi.org/10.1056/nejmra2216691openalex-extracted
Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes
inferredcites →https://doi.org/10.1073/pnas.1217552109openalex-extracted
Atypical angiopoietin-like protein that regulates ANGPTL3
inferredcites →https://doi.org/10.1073/pnas.1315292110openalex-extracted
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis
inferredcites →https://doi.org/10.1073/pnas.1515374112openalex-extracted
Hepatic ANGPTL3 regulates adipose tissue energy homeostasis
inferredcites →https://doi.org/10.1073/pnas.1717420115openalex-extracted
Increased thermogenesis by a noncanonical pathway in ANGPTL3/8-deficient mice
inferredcites →https://doi.org/10.1074/jbc.m203215200openalex-extracted
ANGPTL3 Decreases Very Low Density Lipoprotein Triglyceride Clearance by Inhibition of Lipoprotein Lipase
inferredcites →https://doi.org/10.1074/jbc.m601284200openalex-extracted
Overexpression of Monocyte Chemoattractant Protein-1 in Adipose Tissues Causes Macrophage Recruitment and Insulin Resistance
inferredcites →https://doi.org/10.1097/mol.0000000000000600openalex-extracted
New insights into angiopoietin-like proteins in lipid metabolism and cardiovascular disease risk
inferredcites →https://doi.org/10.1111/jcmm.14488openalex-extracted
Angiopoietin‐like protein 8 expression and association with extracellular matrix metabolism and inflammation during intervertebral disc degeneration
inferredcites →https://doi.org/10.1111/joim.12540openalex-extracted
Adipose tissue regulates insulin sensitivity: role of adipogenesis, de novo lipogenesis and novel lipids
inferredcites →https://doi.org/10.1111/liv.14815openalex-extracted
Genetically engineeredE. coliNissle attenuates hyperammonemia and prevents memory impairment in bile‐duct ligated rats
inferredcites →https://doi.org/10.1152/ajpendo.00084.2012openalex-extracted
Identification of RIFL, a novel adipocyte-enriched insulin target gene with a role in lipid metabolism
inferredcites →https://doi.org/10.1152/ajpendo.00194.2007openalex-extracted
Macrophage TNF-α contributes to insulin resistance and hepatic steatosis in diet-induced obesity
inferredcites →https://doi.org/10.1152/ajpendo.00195.2021openalex-extracted
Regulation of lipoprotein metabolism by ANGPTL3, ANGPTL4, and ANGPTL8
inferredcites →https://doi.org/10.1152/ajpendo.00321.2020openalex-extracted
Differences in metabolic and liver pathobiology induced by two dietary mouse models of nonalcoholic fatty liver disease
inferredcites →https://doi.org/10.1152/ajpendo.90920.2008openalex-extracted
Lipoprotein lipase: from gene to obesity
inferredcites →https://doi.org/10.1152/ajpregu.00137.2012openalex-extracted
Indirect calorimetry in laboratory mice and rats: principles, practical considerations, interpretation and perspectives
inferredcites →https://doi.org/10.1161/atvbaha.108.170316openalex-extracted
Adipose Macrophage Infiltration Is Associated With Insulin Resistance and Vascular Endothelial Dysfunction in Obese Subjects
inferredcites →https://doi.org/10.1172/jci.insight.138777openalex-extracted
ANGPTL8 has both endocrine and autocrine effects on substrate utilization
inferredcites →https://doi.org/10.1172/jci.insight.140294openalex-extracted
Adipose ABHD6 regulates tolerance to cold and thermogenic programs
inferredcites →https://doi.org/10.1172/jci129187openalex-extracted
Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
inferredcites →https://doi.org/10.1172/jci19451openalex-extracted
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
inferredcites →https://doi.org/10.1172/jci26498openalex-extracted
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
inferredcites →https://doi.org/10.1172/jci37118openalex-extracted
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans
inferredcites →https://doi.org/10.1194/jlr.c200010-jlr200openalex-extracted
Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase
inferredcites →https://doi.org/10.1194/jlr.m075689openalex-extracted
ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance
inferredcites →https://doi.org/10.1194/jlr.m800019-jlr200openalex-extracted
Dead adipocytes, detected as crown-like structures, are prevalent in visceral fat depots of genetically obese mice
inferredcites →https://doi.org/10.1194/jlr.ra120000781openalex-extracted
Angiopoietin-like protein 8 differentially regulates ANGPTL3 and ANGPTL4 during postprandial partitioning of fatty acids
inferredcites →https://doi.org/10.1210/en.2004-1565openalex-extracted
Adenosine 5′-Monophosphate-Activated Protein Kinase and p38 Mitogen-Activated Protein Kinase Participate in the Stimulation of Glucose Uptake by Dinitrophenol in Adult Cardiomyocytes
inferredcites →https://doi.org/10.1210/en.2005-0476openalex-extracted
Transgenic Angiopoietin-Like (Angptl)4 Overexpression and Targeted Disruption of Angptl4 and Angptl3: Regulation of Triglyceride Metabolism
inferredcites →https://doi.org/10.1210/jc.2013-3092openalex-extracted
Toll-like Receptor Status in Obesity and Metabolic Syndrome: A Translational Perspective
inferredcites →https://doi.org/10.1677/jme-10-0105openalex-extracted
Apelin stimulates glucose uptake but not lipolysis in human adipose tissue ex vivo
inferredcites →https://doi.org/10.2217/17460875.3.5.545openalex-extracted
Macrophage infiltration into adipose tissue: initiation, propagation and remodeling
inferredcites →https://doi.org/10.2337/db07-0767openalex-extracted
Adipocyte Death, Adipose Tissue Remodeling, and Obesity Complications
inferredcites →https://doi.org/10.3390/cells12212563openalex-extracted
The Proinflammatory Role of ANGPTL8 R59W Variant in Modulating Inflammation through NF-κB Signaling Pathway under TNFα Stimulation
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