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Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
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1 of the 52 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1038/onc.2011.365 (notice 2023-05-23).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/s0002-9440(10)64554-3openalex-snapshotThe Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages
inferredcites →https://doi.org/10.1038/nprot.2007.194openalex-snapshotTandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)—a general method for mapping sites of probe modification in proteomes
inferredcites →https://doi.org/10.1038/onc.2011.365openalex-snapshotRETRACTED ARTICLE: HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs
inferredcites →https://doi.org/10.1038/sj.jcbfm.9600445openalex-snapshotThe NMDA and AMPA/KA Receptors are Involved in Glutamate-Induced Alterations of Occludin Expression and Phosphorylation in Brain Endothelial Cells
inferredcites →https://doi.org/10.1038/srep18928openalex-snapshotOxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation
inferredcites →https://doi.org/10.1042/bj20091609openalex-snapshotInvestigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents
inferredcites →https://doi.org/10.1073/pnas.1214019109openalex-snapshotHypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
inferredcites →https://doi.org/10.1073/pnas.1513433112openalex-snapshotChemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
inferredcites →https://doi.org/10.1074/jbc.m604628200openalex-snapshotThe Length of Peptide Substrates Has a Marked Effect on Hydroxylation by the Hypoxia-inducible Factor Prolyl 4-Hydroxylases
inferredcites →https://doi.org/10.1159/000100812openalex-snapshotSulfasalazine-Induced Reduction of Glutathione Levels in Breast Cancer Cells: Enhancement of Growth-Inhibitory Activity of Doxorubicin
inferredcites →https://doi.org/10.1172/jci64993openalex-snapshotHypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
inferredcites →https://doi.org/10.1172/jci69244openalex-snapshotHypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
inferredcites →https://doi.org/10.1200/jco.20.2.379openalex-snapshotBiologic Correlates of 18Fluorodeoxyglucose Uptake in Human Breast Cancer Measured by Positron Emission Tomography
inferredcites →https://doi.org/10.7150/ijbs.6475openalex-snapshotGlutamate Signaling in Benign and Malignant Disorders: Current Status, Future Perspectives, and Therapeutic Implications
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/cbin.11212openalex-snapshotUp‐regulation of the pentose phosphate pathway and HIF‐1α expression during neural progenitor cell induction following glutamate treatment in rat ex vivo retina
inferred← citeshttps://doi.org/10.1002/ijc.33262openalex-snapshotLoss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice
inferred← citeshttps://doi.org/10.1002/jgm.2998openalex-snapshotCo‐delivery of hypoxia inducible factor‐1α small interfering RNA and 5‐fluorouracil to overcome drug resistance in gastric cancer SGC‐7901 cells
inferred← citeshttps://doi.org/10.1002/mco2.144openalex-snapshotEpithelial–mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities
inferred← citeshttps://doi.org/10.1002/mco2.70556openalex-snapshotNeurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets
inferred← citeshttps://doi.org/10.1002/prca.201800038openalex-snapshotiTRAQ‐Based Quantitative Proteomics Approach Identifies Novel Diagnostic Biomarkers That Were Essential for Glutamine Metabolism and Redox Homeostasis for Gastric Cancer
inferred← citeshttps://doi.org/10.1007/s00428-017-2083-5openalex-snapshotGlutaminase expression is a poor prognostic factor in node-positive triple-negative breast cancer patients with a high level of tumor-infiltrating lymphocytes
inferred← citeshttps://doi.org/10.1007/s12672-025-02790-yopenalex-snapshotGlutamate promotes triple-negative breast cancer development through IRE1α/XBP1-mediated macrophage polarization: mechanism insights and therapy
inferred← citeshttps://doi.org/10.1016/j.cell.2024.03.022openalex-snapshotPositive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
inferred← citeshttps://doi.org/10.1038/s41556-019-0299-0openalex-snapshotExtracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells
inferred← citeshttps://doi.org/10.1080/2162402x.2017.1408746openalex-snapshotA Virus-Like-Particle immunotherapy targeting Epitope-Specific anti-xCT expressed on cancer stem cell inhibits the progression of metastatic cancerin vivo
inferred← citeshttps://doi.org/10.1096/fj.201901384rropenalex-snapshotGPER‐regulated lncRNA‐Glu promotes glutamate secretion to enhance cellular invasion and metastasis in triple‐negative breast cancer
inferred← citeshttps://doi.org/10.1097/cad.0000000000001630openalex-snapshotTargeting xCT with sulfasalazine suppresses triple-negative breast cancer growth via inducing autophagy and coordinating cell cycle and proliferation
inferred← citeshttps://doi.org/10.1101/2022.10.02.510540openalex-snapshotThe MLL3/TP53/PIK3CA cancer driver mutations promote HIF1α-dependent recruitment and differentiation of pro-tumor ICOS hi GITR hi Blimp-1 + effector regulatory T cells in breast tumors
inferred← citeshttps://doi.org/10.1101/606541openalex-snapshotLysosomal cystine mobilization shapes the response of mTORC1 and tissue growth to fasting
inferred← citeshttps://doi.org/10.1101/818245openalex-snapshotGlutathione Peroxidase 8 (GPX8)-IL6 axis is essential in maintaining breast cancer mesenchymal stem-like state and aggressive phenotype
inferred← citeshttps://doi.org/10.1111/cas.15131openalex-snapshotFerroptosis‐related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma
inferred← citeshttps://doi.org/10.1155/2018/4038397openalex-snapshotBeyond the Dual Paraneoplastic Syndromes of Small-Cell Lung Cancer with ADH and ACTH Secretion: A Case Report with Literature Review and Future Implications
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-23-1526openalex-snapshotThe VEGF-Hypoxia Signature Is Upregulated in Basal-like Breast Tumors from Women of African Ancestry and Associated with Poor Outcomes in Breast Cancer
inferred← citeshttps://doi.org/10.1158/2326-6066.c.6550513openalex-snapshotData from Immunotargeting of the xCT Cystine/Glutamate Antiporter Potentiates the Efficacy of HER2-Targeted Immunotherapies in Breast Cancer
inferred← citeshttps://doi.org/10.1186/s11658-024-00682-7openalex-snapshotSystematic and comprehensive insights into HIF-1 stabilization under normoxic conditions: implications for cellular adaptation and therapeutic strategies in cancer
inferred← citeshttps://doi.org/10.1186/s12862-018-1214-1openalex-snapshotCysteine boosters the evolutionary adaptation to CoCl2 mimicked hypoxia conditions, favouring carboplatin resistance in ovarian cancer
inferred← citeshttps://doi.org/10.1186/s40880-017-0248-xopenalex-snapshotChromatin remodeling factor lymphoid-specific helicase inhibits ferroptosis through lipid metabolic genes in lung cancer progression
inferred← citeshttps://doi.org/10.17760/d20621546openalex-snapshotDeveloping oxygen-controlling strategies to boost vaccine immunity and understand hypoxic tumor responses
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3055740/v1openalex-snapshotDisulfidoptosis-related gene SLC7A11, as a potential prognostic and immunological biomarker: Insights from pan-cancer analysis and validation in renal cancer
inferred← citeshttps://doi.org/10.31661/gmj.v8i.1646openalex-snapshotExpression of Bioinformatically Candidate miRNAs including, miR-576-5p, miR-501-3p and miR-3143, Targeting PI3K Pathway in Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.31661/gmj.v8i0.1646openalex-snapshotExpression of Bioinformatically Candidate miRNAs including, miR-576-5p, miR-501-3p and miR-3143, Targeting PI3K Pathway in Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1361992openalex-snapshotMulti-omics analysis-based clinical and functional significance of a novel prognostic and immunotherapeutic gene signature derived from amino acid metabolism pathways in lung adenocarcinoma
inferred← citeshttps://doi.org/10.3389/fonc.2021.744940openalex-snapshotLow Expression of SLC7A11 Confers Drug Resistance and Worse Survival in Ovarian Cancer via Inhibition of Cell Autophagy as a Competing Endogenous RNA
inferred← citeshttps://doi.org/10.3389/fonc.2024.1492498openalex-snapshotClinicopathological characteristics of invasive stratified mucinous carcinoma of the cervix and the expression and clinical significance of SLC7A11, SLC3A2 and PD-L1
inferred← citeshttps://doi.org/10.3389/fphar.2021.667433openalex-snapshotQian Yang Yu Yin Granule Improves Renal Injury of Hypertension by Regulating Metabolic Reprogramming Mediated by HIF-1α/PKM2 Positive Feedback Loop
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