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1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Predictors of New-Onset Kidney Disease in a Community-Based Population

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Genotype Imputation in Genome‐Wide Association Studies

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MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

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Five Years of GWAS Discovery

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Hydrodynamic structure of bovine serum albumin determined by transient electric birefringence

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Evolving importance of kidney disease: from subspecialty to global health burden

inferredcites →https://doi.org/10.1038/75556openalex-snapshot

Gene Ontology: tool for the unification of biology

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Genome-wide linkage analysis of serum creatinine in three isolated European populations

inferredcites →https://doi.org/10.1038/nature09298openalex-snapshot

Integrating common and rare genetic variation in diverse human populations

inferredcites →https://doi.org/10.1038/nature11632openalex-snapshot

An integrated map of genetic variation from 1,092 human genomes

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A global reference for human genetic variation

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A human phenome-interactome network of protein complexes implicated in genetic disorders

inferredcites →https://doi.org/10.1038/ncomms10023openalex-snapshot

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

inferredcites →https://doi.org/10.1038/ncomms6890openalex-snapshot

Biological interpretation of genome-wide association studies using predicted gene functions

inferredcites →https://doi.org/10.1038/ng.2213openalex-snapshot

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

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Systematic identification of trans eQTLs as putative drivers of known disease associations

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Gene expression analysis identifies global gene dosage sensitivity in cancer

inferredcites →https://doi.org/10.1038/ng.3390openalex-snapshot

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

inferredcites →https://doi.org/10.1038/ng.3396openalex-snapshot

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

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A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

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The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

inferredcites →https://doi.org/10.1038/ng.377openalex-snapshot

Multiple loci associated with indices of renal function and chronic kidney disease

inferredcites →https://doi.org/10.1038/ng.566openalex-snapshot

Genetic loci influencing kidney function and chronic kidney disease

inferredcites →https://doi.org/10.1038/ng.568openalex-snapshot

New loci associated with kidney function and chronic kidney disease

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A new multipoint method for genome-wide association studies by imputation of genotypes

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Common noncoding UMOD gene variants induce salt-sensitive hypertension and kidney damage by increasing uromodulin expression

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Calibration and random variation of the serum creatinine assay as critical elements of using equations to estimate glomerular filtration rate

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Estimating GFR Using Serum Cystatin C Alone and in Combination With Serum Creatinine: A Pooled Analysis of 3,418 Individuals With CKD

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KORA-gen - Resource for Population Genetics, Controls and a Broad Spectrum of Disease Phenotypes

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PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses

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METAL: fast and efficient meta-analysis of genomewide association scans

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GWAtoolbox: an R package for fast quality control and handling of genome-wide association studies meta-analysis data

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minimac2: faster genotype imputation

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LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

inferredcites →https://doi.org/10.1093/hmg/dds369openalex-snapshot

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function

inferredcites →https://doi.org/10.1093/hmg/ddu399openalex-snapshot

Rare mutations associating with serum creatinine and chronic kidney disease

inferredcites →https://doi.org/10.1093/ije/dym273openalex-snapshot

Cohort Profile: The Dutch 'TRacking Adolescents' Individual Lives' Survey'; TRAILS

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Reactome: a database of reactions, pathways and biological processes

inferredcites →https://doi.org/10.1093/nar/gkr988openalex-snapshot

KEGG for integration and interpretation of large-scale molecular data sets

inferredcites →https://doi.org/10.1093/nar/gkt1225openalex-snapshot

The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse

inferredcites →https://doi.org/10.1097/01.asn.0000135972.13396.6fopenalex-snapshot

Genomewide Linkage Analysis to Serum Creatinine, GFR, and Creatinine Clearance in a Community-Based Population

inferredcites →https://doi.org/10.1101/gr.137323.112openalex-snapshot

Annotation of functional variation in personal genomes using RegulomeDB

inferredcites →https://doi.org/10.1101/gr.182881.114openalex-snapshot

Shroom3 contributes to the maintenance of the glomerular filtration barrier integrity

inferredcites →https://doi.org/10.1111/j.0006-341x.1999.00997.xopenalex-snapshot

Genomic Control for Association Studies

inferredcites →https://doi.org/10.1126/science.1136800openalex-snapshot

Clustering by Passing Messages Between Data Points

inferredcites →https://doi.org/10.1136/bmj.327.7414.557openalex-snapshot

Measuring inconsistency in meta-analyses

inferredcites →https://doi.org/10.1159/000326901openalex-snapshot

Chronic Kidney Disease: Novel Insights from Genome-Wide Association Studies

inferredcites →https://doi.org/10.1371/journal.pgen.1002584openalex-snapshot

Genome-Wide Association and Functional Follow-Up Reveals New Loci for Kidney Function

inferredcites →https://doi.org/10.1371/journal.pgen.1005230openalex-snapshot

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

inferredcites →https://doi.org/10.1371/journal.pone.0064343openalex-snapshot

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation

inferredcites →https://doi.org/10.7326/0003-4819-130-6-199903160-00002openalex-snapshot

A More Accurate Method To Estimate Glomerular Filtration Rate from Serum Creatinine: A New Prediction Equation

inferredcites →https://doi.org/10.7326/0003-4819-145-4-200608150-00004openalex-snapshot

Using Standardized Serum Creatinine Values in the Modification of Diet in Renal Disease Study Equation for Estimating Glomerular Filtration Rate

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.3389/fgene.2021.711155openalex-snapshot

Pathway Association Studies Reveal Gene Loci and Pathway Networks that Associated With Plasma Cystatin C Levels

inferred← citeshttps://doi.org/10.3389/fgene.2021.716151openalex-snapshot

Investigation of FADS Gene Cluster Single Nucleotide Polymorphisms in End-Stage Renal Disease Compared With Normal Controls

inferred← citeshttps://doi.org/10.3389/fgene.2021.794246openalex-snapshot

Corrigendum: Genetically Predicted Fibroblast Growth Factor 23 and Major Cardiovascular Diseases, Their Risk Factors, Kidney Function, and Longevity: A Two-Sample Mendelian Randomization Study

inferred← citeshttps://doi.org/10.3389/fgene.2024.1372042openalex-snapshot

Genetic association and transferability for urinary albumin-creatinine ratio as a marker of kidney disease in four Sub-Saharan African populations and non-continental individuals of African ancestry

inferred← citeshttps://doi.org/10.3389/fimmu.2019.02171openalex-snapshot

Protective and Regenerative Roles of T Cells in Central Nervous System Disorders

inferred← citeshttps://doi.org/10.3389/ti.2024.13317openalex-snapshot

Novel Aspects of Immunogenetics and Post-Transplant Events in Kidney Transplantation

inferred← citeshttps://doi.org/10.3390/cancers13081864openalex-snapshot

Genetic Analysis Reveals Rare Variants in T-Cell Response Gene MR1 Associated with Poor Overall Survival after Urothelial Cancer Diagnosis

inferred← citeshttps://doi.org/10.3390/genes14030609openalex-snapshot

Harnessing Genomic Analysis to Explore the Role of Telomeres in the Pathogenesis and Progression of Diabetic Kidney Disease

inferred← citeshttps://doi.org/10.3410/f.734486771.793554174openalex-snapshot

Faculty Opinions recommendation of Molecular insights into genome-wide association studies of chronic kidney disease-defining traits.

inferred← citeshttps://doi.org/10.3410/f.739382438.793583091openalex-snapshot

Faculty Opinions recommendation of Genetics of 35 blood and urine biomarkers in the UK Biobank.

inferred← citeshttps://doi.org/10.64898/2026.01.15.26344229openalex-snapshot

Integrative kidney multi-omics traces genetic drivers of chronic kidney disease to targets within the renal epigenome, transcriptome and proteome

inferred← citeshttps://doi.org/10.64898/2026.02.19.26346652openalex-snapshot

The KD Atlas: A Multi-Omics Network Resource for Kidney Disease Research

inferred← citeshttps://doi.org/10.7554/elife.86129openalex-snapshot

Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15

inferred← citeshttps://doi.org/10.7717/peerj.4466openalex-snapshot

Global analysis of A-to-I RNA editing reveals association with common disease variants

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