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Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

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Outgoing claims: the papers this work cites, builds on, or argues with.

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A Multiancestral Genome-Wide Exome Array Study of Alzheimer Disease, Frontotemporal Dementia, and Progressive Supranuclear Palsy
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inferredcites →https://doi.org/10.1038/ejhg.2011.10openalex-snapshot
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Integrating common and rare genetic variation in diverse human populations
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An integrated encyclopedia of DNA elements in the human genome
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An integrated map of genetic variation from 1,092 human genomes
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New genetic loci link adipose and insulin biology to body fat distribution
inferredcites →https://doi.org/10.1038/nature14177openalex-snapshot
Genetic studies of body mass index yield new insights for obesity biology
inferredcites →https://doi.org/10.1038/nbt.1662openalex-snapshot
Discovery and characterization of chromatin states for systematic annotation of the human genome
inferredcites →https://doi.org/10.1038/ncomms6897openalex-snapshot
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
inferredcites →https://doi.org/10.1038/ng.1086openalex-snapshot
Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations
inferredcites →https://doi.org/10.1038/ng.1087openalex-snapshot
Meta-analysis identifies common variants associated with body mass index in east Asians
inferredcites →https://doi.org/10.1038/ng.156openalex-snapshot
Common genetic variation near MC4R is associated with waist circumference and insulin resistance
inferredcites →https://doi.org/10.1038/ng.2213openalex-snapshot
Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits
inferredcites →https://doi.org/10.1038/ng.2274openalex-snapshot
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
inferredcites →https://doi.org/10.1038/ng.2354openalex-snapshot
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
inferredcites →https://doi.org/10.1038/ng.2383openalex-snapshot
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
inferredcites →https://doi.org/10.1038/ng.2385openalex-snapshot
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
inferredcites →https://doi.org/10.1038/ng.2435openalex-snapshot
Bayesian refinement of association signals for 14 loci in 3 common diseases
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Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion
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Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
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A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry
inferredcites →https://doi.org/10.1038/ng.287openalex-snapshot
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
inferredcites →https://doi.org/10.1038/ng.2870openalex-snapshot
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
inferredcites →https://doi.org/10.1038/ng.290openalex-snapshot
Variants in MTNR1B influence fasting glucose levels
inferredcites →https://doi.org/10.1038/ng.357openalex-snapshot
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits
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New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
inferredcites →https://doi.org/10.1038/ng.608openalex-snapshot
Common SNPs explain a large proportion of the heritability for human height
inferredcites →https://doi.org/10.1038/ng.685openalex-snapshot
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
inferredcites →https://doi.org/10.1038/ng.686openalex-snapshot
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
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Evaluating coverage of genome-wide association studies
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A method and server for predicting damaging missense mutations
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Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm
inferredcites →https://doi.org/10.1038/nprot.2014.071openalex-snapshot
Quality control and conduct of genome-wide association meta-analyses
inferredcites →https://doi.org/10.1038/nrg2796openalex-snapshot
Genotype imputation for genome-wide association studies
inferredcites →https://doi.org/10.1038/oby.2011.154openalex-snapshot
Genome‐Wide Association of BMI in African Americans
inferredcites →https://doi.org/10.1056/nejmoa0801891openalex-snapshot
General and Abdominal Adiposity and Risk of Death in Europe
inferredcites →https://doi.org/10.1086/321272openalex-snapshot
Are Rare Variants Responsible for Susceptibility to Complex Diseases?
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A Bayesian Measure of the Probability of False Discovery in Genetic Epidemiology Studies
inferredcites →https://doi.org/10.1093/bfgp/elu012openalex-snapshot
Methodology for the analysis of rare genetic variation in genome-wide association and re-sequencing studies of complex human traits
inferredcites →https://doi.org/10.1093/bioinformatics/btp324openalex-snapshot
Fast and accurate short read alignment with Burrows–Wheeler transform
inferredcites →https://doi.org/10.1093/bioinformatics/bts724openalex-snapshot
A comprehensive SNP and indel imputability database
inferredcites →https://doi.org/10.1093/hmg/ddu175openalex-snapshot
No large-effect low-frequency coding variation found for myocardial infarction
inferredcites →https://doi.org/10.1093/nar/gkr917openalex-snapshot
HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants
inferredcites →https://doi.org/10.1101/gr.135350.111openalex-snapshot
GENCODE: The reference human genome annotation for The ENCODE Project
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Genomic Control for Association Studies
inferredcites →https://doi.org/10.1159/000353879openalex-snapshot
Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
inferredcites →https://doi.org/10.1161/circulationaha.109.192574openalex-snapshot
Mortality, Health Outcomes, and Body Mass Index in the Overweight Range
inferredcites →https://doi.org/10.1167/iovs.14-15204openalex-snapshot
Exome Array Analysis Identifies CAV1/CAV2 as a Susceptibility Locus for Intraocular Pressure
inferredcites →https://doi.org/10.1172/jci7231openalex-snapshot
The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
inferredcites →https://doi.org/10.1186/1471-2105-11-288openalex-snapshot
GWAMA: software for genome-wide association meta-analysis
inferredcites →https://doi.org/10.1194/jlr.p041673openalex-snapshot
Heritability of metabolic syndrome traits in a large population-based sample
inferredcites →https://doi.org/10.1371/journal.pbio.1000294openalex-snapshot
Rare Variants Create Synthetic Genome-Wide Associations
inferredcites →https://doi.org/10.1371/journal.pgen.1000529openalex-snapshot
A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies
inferredcites →https://doi.org/10.1371/journal.pgen.1004876openalex-snapshot
Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus
inferredcites →https://doi.org/10.1371/journal.pone.0000841openalex-snapshot
Heterogeneity in Meta-Analyses of Genome-Wide Association Investigations
inferredcites →https://doi.org/10.1371/journal.pone.0046688openalex-snapshot
Predicting the Functional Effect of Amino Acid Substitutions and Indels
inferredcites →https://doi.org/10.2337/diabetes.54.1.275openalex-snapshot
Heritability of Insulin Secretion, Peripheral and Hepatic Insulin Action, and Intracellular Glucose Partitioning in Young and Old Danish Twins
inferredcites →https://doi.org/10.2337/diacare.14.3.173openalex-snapshot
Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease
inferredcites →https://doi.org/10.2337/diacare.26.11.3160openalex-snapshot
Follow-up Report on the Diagnosis of Diabetes Mellitus

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Integration of human pancreatic islet genomic data refines regulatory mechanisms at Type 2 Diabetes susceptibility loci
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