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Stress-Responsive Sestrins Link p53 with Redox Regulation and Mammalian Target of Rapamycin Signaling

https://doi.org/10.1089/ars.2010.3530

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Exercise improves glucose uptake in murine myotubes through the AMPKα2-mediated induction of Sestrins

inferred← citeshttps://doi.org/10.1016/j.bbamcr.2020.118845openalex-snapshot

Acute depletion of telomerase components DKC1 and NOP10 induces oxidative stress and disrupts ribosomal biogenesis via NPM1 and activation of the P53 pathway

inferred← citeshttps://doi.org/10.1016/j.bcp.2012.06.004openalex-snapshot

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125

inferred← citeshttps://doi.org/10.1016/j.biopha.2023.116114openalex-snapshot

Theaflavin pretreatment ameliorates renal ischemia/reperfusion injury by attenuating apoptosis and oxidative stress in vivo and in vitro

inferred← citeshttps://doi.org/10.1016/j.canlet.2021.06.015openalex-snapshot

Suppression of oxidative phosphorylation and IDH2 sensitizes colorectal cancer to a naphthalimide derivative and mitoxantrone

inferred← citeshttps://doi.org/10.1016/j.cbi.2023.110405openalex-snapshot

Malathion alters the transcription of target genes of the tumour suppressor tp53 and cancerous processes in Colossoma macropomum: Mechanisms of DNA damage response, oxidative stress and apoptosis

inferred← citeshttps://doi.org/10.1016/j.cbi.2025.111756openalex-snapshot

Sirtuin 1/3 regulates p53 deacetylation to inhibit iron poisoning-induced alveolar epithelial cell death and contributes to Rapamycin-mediated protection against limb ischemia/reperfusion-induced lung injury

inferred← citeshttps://doi.org/10.1016/j.cell.2012.02.028openalex-snapshot

Single-Cell Exome Sequencing and Monoclonal Evolution of a JAK2-Negative Myeloproliferative Neoplasm

inferred← citeshttps://doi.org/10.1016/j.cellsig.2012.09.004openalex-snapshot

Upregulation of sestrin 2 expression via JNK pathway activation contributes to autophagy induction in cancer cells

inferred← citeshttps://doi.org/10.1016/j.celrep.2014.10.019openalex-snapshot

Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex

inferred← citeshttps://doi.org/10.1016/j.celrep.2020.107897openalex-snapshot

A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma

inferred← citeshttps://doi.org/10.1016/j.celrep.2021.110069openalex-snapshot

Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

inferred← citeshttps://doi.org/10.1016/j.clinbiochem.2016.02.002openalex-snapshot

Sestrin-2 is significantly increased in malignant pleural effusions due to lung cancer and is potentially secreted by pleural mesothelial cells

inferred← citeshttps://doi.org/10.1016/j.critrevonc.2025.104820openalex-snapshot

Autophagy and oxidative stress in solid tumors: Mechanisms and therapeutic opportunities

inferred← citeshttps://doi.org/10.1016/j.exger.2012.12.011openalex-snapshot

SESN-1 is a positive regulator of lifespan in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.exger.2017.07.009openalex-snapshot

Physical exercise increases Sestrin 2 protein levels and induces autophagy in the skeletal muscle of old mice

inferred← citeshttps://doi.org/10.1016/j.exger.2018.05.006openalex-snapshot

Sestrins are differentially expressed with age in the skeletal muscle of men: A cross-sectional analysis

inferred← citeshttps://doi.org/10.1016/j.expneurol.2013.12.009openalex-snapshot

Induction of sestrin2 as an endogenous protective mechanism against amyloid beta-peptide neurotoxicity in primary cortical culture

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2012.07.011openalex-snapshot

Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2013.02.009openalex-snapshot

Prostate cancer and physical activity: Adaptive response to oxidative stress

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2015.06.043openalex-snapshot

Perfluorooctanoic acid exposure induces endoplasmic reticulum stress in the liver and its effects are ameliorated by 4-phenylbutyrate

inferred← citeshttps://doi.org/10.1016/j.jphs.2020.11.012openalex-snapshot

Sestrin2 protects against bavachin induced ER stress through AMPK/mTORC1 signaling pathway in HepG2 cells

inferred← citeshttps://doi.org/10.1016/j.jsbmb.2012.09.011openalex-snapshot

1,25-Dihydroxyvitamin D3 and the aging-related Forkhead Box O and Sestrin proteins in osteoblasts

inferred← citeshttps://doi.org/10.1016/j.lfs.2017.12.023openalex-snapshot

The role of physical exercise on Sestrin1 and 2 accumulations in the skeletal muscle of mice

inferred← citeshttps://doi.org/10.1016/j.mad.2020.111251openalex-snapshot

The role of Sestrins in the regulation of the aging process

inferred← citeshttps://doi.org/10.1016/j.mad.2020.111379openalex-snapshot

Sestrin family – the stem controlling healthy ageing

inferred← citeshttps://doi.org/10.1016/j.matpr.2021.05.175openalex-snapshot

WITHDRAWN: Biochemical and molecular study of the effect of chitosan nanoparticles against hydroxy apatite nanoparticles

inferred← citeshttps://doi.org/10.1016/j.molonc.2013.07.010openalex-snapshot

Nelfinavir and bortezomib inhibit mTOR activity via ATF4‐mediated sestrin‐2 regulation

inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2014.08.004openalex-snapshot

Oxidative stress preferentially induces a subtype of micronuclei and mediates the genomic instability caused by p53 dysfunction

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2019.05.005openalex-snapshot

Sestrin2 overexpression attenuates focal cerebral ischemic injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis

inferred← citeshttps://doi.org/10.1016/j.phrs.2020.104990openalex-snapshot

Sestrin2 as a potential therapeutic target for cardiovascular diseases

inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105331openalex-snapshot

Regulatory mechanisms of Sesn2 and its role in multi-organ diseases

inferred← citeshttps://doi.org/10.1016/j.phyplu.2021.100133openalex-snapshot

Phytochemical based sestrin2 pharmacological modulators in the treatment of adenocarcinomas

inferred← citeshttps://doi.org/10.1016/j.pnpbp.2017.11.020openalex-snapshot

Glucocorticoids, genes and brain function

inferred← citeshttps://doi.org/10.1016/j.redox.2015.09.039openalex-snapshot

The balance of powers: Redox regulation of fibrogenic pathways in kidney injury

inferred← citeshttps://doi.org/10.1016/j.redox.2018.04.003openalex-snapshot

The phosphorylated redox proteome of Chlamydomonas reinhardtii: Revealing novel means for regulation of protein structure and function

inferred← citeshttps://doi.org/10.1016/j.tjnut.2022.11.021openalex-snapshot

Glucose-Induced Activation of mTORC1 is Associated with Hexokinase2 Binding to Sestrins in HEK293T Cells

inferred← citeshttps://doi.org/10.1016/j.tox.2014.10.009openalex-snapshot

Autophagy and senescence, stress responses induced by the DNA-damaging mycotoxin alternariol

inferred← citeshttps://doi.org/10.1038/cdd.2012.13openalex-snapshot

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice

inferred← citeshttps://doi.org/10.1038/nrc3711openalex-snapshot

Unravelling mechanisms of p53-mediated tumour suppression

inferred← citeshttps://doi.org/10.1038/onc.2015.222openalex-snapshot

ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer

inferred← citeshttps://doi.org/10.1038/s12276-022-00737-9openalex-snapshot

Sestrin2 protects against cholestatic liver injury by inhibiting endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis

inferred← citeshttps://doi.org/10.1038/s41419-021-03392-6openalex-snapshot

Autophagy augments the self-renewal of lung cancer stem cells by the degradation of ubiquitinated p53

inferred← citeshttps://doi.org/10.1038/s41419-026-09067-4openalex-snapshot

mTORC1 suppression by Trp53 mutation drives resistance to immune checkpoint blockade

inferred← citeshttps://doi.org/10.1038/s41420-023-01411-3openalex-snapshot

Sestrin2-mediated disassembly of stress granules dampens aerobic glycolysis to overcome glucose starvation

inferred← citeshttps://doi.org/10.1038/s41568-020-0262-1openalex-snapshot

p53: 800 million years of evolution and 40 years of discovery

inferred← citeshttps://doi.org/10.1038/s41598-017-19102-2openalex-snapshot

SESN2 facilitates mitophagy by helping Parkin translocation through ULK1 mediated Beclin1 phosphorylation

inferred← citeshttps://doi.org/10.1038/srep22538openalex-snapshot

Sestrin2 is induced by glucose starvation via the unfolded protein response and protects cells from non-canonical necroptotic cell death

inferred← citeshttps://doi.org/10.1042/cs20140336openalex-snapshot

Role of NADPH oxidase in the regulation of autophagy in cardiomyocytes

inferred← citeshttps://doi.org/10.1073/pnas.1311947110openalex-snapshot

Loss of caspase-2 augments lymphomagenesis and enhances genomic instability in Atm -deficient mice

inferred← citeshttps://doi.org/10.1074/jbc.m113.457242openalex-snapshot

Identification of a Novel Endoplasmic Reticulum Stress Response Element Regulated by XBP1

inferred← citeshttps://doi.org/10.1074/jbc.m114.595397openalex-snapshot

Sestrin2 Protein Positively Regulates AKT Enzyme Signaling and Survival in Human Squamous Cell Carcinoma and Melanoma Cells

inferred← citeshttps://doi.org/10.1080/02656736.2018.1496282openalex-snapshot

Suppression of SESN1 reduces cisplatin and hyperthermia resistance through increasing reactive oxygen species (ROS) in human maxillary cancer cells

inferred← citeshttps://doi.org/10.1080/09513590.2022.2163234openalex-snapshot

Could sestrin protein in serum be a new marker of oxidative stress in patients with polycystic ovary syndrome?

inferred← citeshttps://doi.org/10.1080/14728222.2017.1279147openalex-snapshot

Targeting protein kinase-b3 (akt3) signaling in melanoma

inferred← citeshttps://doi.org/10.1080/15384101.2015.1084447openalex-snapshot

Sestrin2 facilitates death receptor-induced apoptosis in lung adenocarcinoma cells through regulation of XIAP degradation

inferred← citeshttps://doi.org/10.1080/15548627.2016.1179403openalex-snapshot

SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers

inferred← citeshttps://doi.org/10.1089/ars.2016.6664openalex-snapshot

Diabetes and Kidney Disease: Role of Oxidative Stress

inferred← citeshttps://doi.org/10.1089/ars.2021.0098openalex-snapshot

Reactive Oxygen Species-Mediated Diabetic Heart Disease: Mechanisms and Therapies

inferred← citeshttps://doi.org/10.1093/braincomms/fcaa130openalex-snapshot

Implication of sestrin3 in epilepsy and its comorbidities

inferred← citeshttps://doi.org/10.1093/neuonc/noz175.248openalex-snapshot

COMP-05. A DRUG ASSOCIATION MAP OF GLIOBLASTOMA INFORMS PRECISION TARGETING OF p53-DEPENDENT METABOLIC STATES

inferred← citeshttps://doi.org/10.1101/811638openalex-snapshot

Physical activity improves sarcopenia in a murine model by enhancing the proliferative potential of muscle stem cells, oxidative capacity of mitochondrial enzymes and expression of Sestrins

inferred← citeshttps://doi.org/10.1101/cshperspect.a019141openalex-snapshot

The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control

inferred← citeshttps://doi.org/10.1101/cshperspect.a026146openalex-snapshot

Regulation of Cellular Metabolism and Hypoxia by p53

inferred← citeshttps://doi.org/10.1101/gad.340919.120openalex-snapshot

mTOR inhibition acts as an unexpected checkpoint in p53-mediated tumor suppression

inferred← citeshttps://doi.org/10.1104/pp.112.199992openalex-snapshot

Reactive Oxygen Species and Autophagy in Plants and Algae

inferred← citeshttps://doi.org/10.1111/1440-1681.13231openalex-snapshot

Inhibition of microRNA‐148b‐3p alleviates oxygen‐glucose deprivation/reoxygenation‐induced apoptosis and oxidative stress in HT22 hippocampal neuron via reinforcing Sestrin2/Nrf2 signalling

inferred← citeshttps://doi.org/10.1111/aji.13222openalex-snapshot

Sestrin2 alleviates palmitate‐induced endoplasmic reticulum stress, apoptosis, and defective invasion of human trophoblast cells

inferred← citeshttps://doi.org/10.1111/cns.14664openalex-snapshot

SESN1 functions as a new tumor suppressor gene via Toll‐like receptor signaling pathway in neuroblastoma

inferred← citeshttps://doi.org/10.1111/jcmm.16540openalex-snapshot

Sestrin2 as a gatekeeper of cellular homeostasis: Physiological effects for the regulation of hypoxia‐related diseases

inferred← citeshttps://doi.org/10.1111/jfbc.12708openalex-snapshot

Protective effects of hawthorn (Crataegus pinnatifida ) polyphenol extract against UVB-induced skin damage by modulating the p53 mitochondrial pathway in vitro and in vivo

inferred← citeshttps://doi.org/10.1111/php.12624openalex-snapshot

Distinct Role of Sesn2 in Response to UVB‐Induced DNA Damage and UVA‐Induced Oxidative Stress in Melanocytes

inferred← citeshttps://doi.org/10.1128/mcb.00217-13openalex-snapshot

Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression

inferred← citeshttps://doi.org/10.1134/s0026893318060043openalex-snapshot

Sestrins are Gatekeepers in the Way from Stress to Aging and Disease

inferred← citeshttps://doi.org/10.1134/s0026898418060046openalex-snapshot

Cестрины – шлагбаумы на путях от стресса к старению и болезням

inferred← citeshttps://doi.org/10.1134/s2079086422040028openalex-snapshot

The Role of Sestrins in the Regulation of the Cellular Response to Stress

inferred← citeshttps://doi.org/10.1136/bjophthalmol-2017-311283openalex-snapshot

Immunohistochemical evaluation of stress-responsive protein sestrin2 and its correlation with p53 mutational status in eyelid sebaceous gland carcinoma

inferred← citeshttps://doi.org/10.1152/ajpendo.00212.2013openalex-snapshot

Sestrin 3 regulation in type 2 diabetic patients and its influence on metabolism and differentiation in skeletal muscle

inferred← citeshttps://doi.org/10.1152/ajpgi.00135.2017openalex-snapshot

Exocrine pancreas glutamate secretion help to sustain enterocyte nutritional needs under protein restriction

inferred← citeshttps://doi.org/10.1152/ajpheart.00008.2019openalex-snapshot

Cardioprotective roles of sestrin 1 and sestrin 2 against doxorubicin cardiotoxicity

inferred← citeshttps://doi.org/10.1152/ajprenal.00135.2013openalex-snapshot

mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN

inferred← citeshttps://doi.org/10.1152/ajprenal.00625.2013openalex-snapshot

Expression of a novel stress-inducible protein, sestrin 2, in rat glomerular parietal epithelial cells

inferred← citeshttps://doi.org/10.1155/2017/3296294openalex-snapshot

Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases

inferred← citeshttps://doi.org/10.1155/2019/8127362openalex-snapshot

Emerging Perspective: Role of Increased ROS and Redox Imbalance in Skin Carcinogenesis

inferred← citeshttps://doi.org/10.1155/2020/6039769openalex-snapshot

Functional Role of p53 in the Regulation of Chemical-Induced Oxidative Stress

inferred← citeshttps://doi.org/10.1155/2021/6970578openalex-snapshot

Banhasasim‐Tang Ameliorates Spatial Memory by Suppressing Oxidative Stress through Regulation of ERK/p38 Signaling in Hippocampus of Mice

inferred← citeshttps://doi.org/10.1159/000487970openalex-snapshot

Sestrin-Mediated Inhibition of Stress-Induced Intervertebral Disc Degradation Through the Enhancement of Autophagy

inferred← citeshttps://doi.org/10.1177/1753425918785715openalex-snapshot

Human breast milk-derived exosomes attenuate cell death in intestinal epithelial cells

inferred← citeshttps://doi.org/10.1186/s11658-021-00302-8openalex-snapshot

The functions and roles of sestrins in regulating human diseases

inferred← citeshttps://doi.org/10.1186/s12864-021-07645-8openalex-snapshot

Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.1186/s12935-022-02498-xopenalex-snapshot

Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer

inferred← citeshttps://doi.org/10.1186/s12964-025-02104-3openalex-snapshot

p53-regulated SESN1 and SESN2 regulate cell proliferation and cell death through control of STAT3

inferred← citeshttps://doi.org/10.1186/s12964-025-02502-7openalex-snapshot

Extracellular vesicles from long COVID patients promote RUNX2-mediated cellular stress via dysregulated miR-204 and p53 pathway activation

inferred← citeshttps://doi.org/10.1186/s12967-017-1297-2openalex-snapshot

p53: key conductor of all anti-acne therapies

inferred← citeshttps://doi.org/10.1186/s12986-017-0212-4openalex-snapshot

Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer

inferred← citeshttps://doi.org/10.1186/s13223-019-0360-3openalex-snapshot

Sestrin2 is involved in asthma: a case–control study

inferred← citeshttps://doi.org/10.1186/s40001-025-03580-6openalex-snapshot

Sestrin2 ameliorates LPS-induced cardiomyocyte injury by inhibiting ferroptosis via the Nrf2/HO-1 pathway

inferred← citeshttps://doi.org/10.1371/journal.pone.0032035openalex-snapshot

Sestrin2 Modulates AMPK Subunit Expression and Its Response to Ionizing Radiation in Breast Cancer Cells

inferred← citeshttps://doi.org/10.1371/journal.pone.0126830openalex-snapshot

Identification of Sestrin3 Involved in the In vitro Resistance of Colorectal Cancer Cells to Irinotecan

inferred← citeshttps://doi.org/10.1515/biol-2025-1092openalex-snapshot

Therapeutic approaches for liver fibrosis/cirrhosis by targeting pyroptosis

inferred← citeshttps://doi.org/10.1515/tnsci-2020-0118openalex-snapshot

Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity

inferred← citeshttps://doi.org/10.15252/embr.202152707openalex-snapshot

LncPSCA in the 8q24.3 risk locus drives gastric cancer through destabilizing DDX5

inferred← citeshttps://doi.org/10.1534/g3.115.017699openalex-snapshot

Transcriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq

inferred← citeshttps://doi.org/10.1590/0004-282x-anp-2021-0202openalex-snapshot

Possible roles of sestrin2 in multiple sclerosis and its relationships with clinical outcomes

inferred← citeshttps://doi.org/10.18632/oncotarget.27367openalex-snapshot

p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis

inferred← citeshttps://doi.org/10.18632/oncotarget.759openalex-snapshot

The Interfaces Between Signal Transduction Pathways: IGF-1/mTor, p53 and the Parkinson Disease Pathway

inferred← citeshttps://doi.org/10.18632/oncotarget.9112openalex-snapshot

Nuclear receptor 4A1 (NR4A1) as a drug target for treating rhabdomyosarcoma (RMS)

inferred← citeshttps://doi.org/10.20455/ros.2016.805openalex-snapshot

ROS-Inducing Agents for Cancer Chemotherapy

inferred← citeshttps://doi.org/10.21203/rs.3.rs-10046163/v1openalex-snapshot

Loss of endothelial cell FAK represses cisplatin-induced vascular senescence in distal niches to reduce lung metastatic burden

inferred← citeshttps://doi.org/10.21203/rs.3.rs-133589/v1openalex-snapshot

Comprehensive Analysis of Differentially Expressed CircRNAs and CeRNA Regulatory Network in Porcine Skeletal Muscle

inferred← citeshttps://doi.org/10.22038/ijbms.2018.18283.4923openalex-snapshot

Radiosensitizing effects of Sestrin2 in PC3 prostate cancer cells.

inferred← citeshttps://doi.org/10.25279/sak.991294openalex-snapshot

Nörodejeneratif Hastalıklarda Umut Verici Bir Terapötik Hedef: Sestrin-2

inferred← citeshttps://doi.org/10.26686/wgtn.17134208openalex-snapshot

An investigation into growth-related genes in the Australasian snapper, Chrysophrys auratus

inferred← citeshttps://doi.org/10.29252/nkjmd-120413openalex-snapshot

اثر تمرین تداومی با شدت متوسط بر شاخصهای اتوفاژی عضله اسکلتی در رت های نر سالمند نژاد ویستار

inferred← citeshttps://doi.org/10.31083/fbl45346openalex-snapshot

The Dual Role of Autophagy in Lung Cancer: From Molecular Mechanisms to Metabolic Regulation and Targeted Therapy Strategies

inferred← citeshttps://doi.org/10.3233/jad-160479openalex-snapshot

Relative Alterations in Blood-Based Levels of Sestrin in Alzheimer’s Disease and Mild Cognitive Impairment Patients

inferred← citeshttps://doi.org/10.32920/21982901openalex-snapshot

The Lysosome Signaling Platform: Adapting With the Times

inferred← citeshttps://doi.org/10.32920/21982901.v1openalex-snapshot

The Lysosome Signaling Platform: Adapting With the Times

inferred← citeshttps://doi.org/10.3389/fcell.2019.00113openalex-snapshot

The Lysosome Signaling Platform: Adapting With the Times

inferred← citeshttps://doi.org/10.3389/fcell.2020.548605openalex-snapshot

Histone Demethylase JMJD3 Mediated Doxorubicin-Induced Cardiomyopathy by Suppressing SESN2 Expression

inferred← citeshttps://doi.org/10.3389/fcell.2020.603421openalex-snapshot

SESTRINs: Emerging Dynamic Stress-Sensors in Metabolic and Environmental Health

inferred← citeshttps://doi.org/10.3389/fendo.2021.751020openalex-snapshot

Sestrin2 as a Potential Target for Regulating Metabolic-Related Diseases

inferred← citeshttps://doi.org/10.3389/fgene.2020.00593openalex-snapshot

Searching for the Mechanisms of Mammalian Cellular Aging Through Underlying Gene Regulatory Networks

inferred← citeshttps://doi.org/10.3389/fonc.2012.00171openalex-snapshot

The interplay between autophagy and ROS in tumorigenesis

inferred← citeshttps://doi.org/10.3389/fonc.2022.852424openalex-snapshot

Crosstalk Between ROS and Autophagy in Tumorigenesis: Understanding the Multifaceted Paradox

inferred← citeshttps://doi.org/10.3389/fonc.2022.958155openalex-snapshot

Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation

inferred← citeshttps://doi.org/10.3389/fphar.2020.580407openalex-snapshot

CC-223, NSC781406, and BGT226 Exerts a Cytotoxic Effect Against Pancreatic Cancer Cells via mTOR Signaling

inferred← citeshttps://doi.org/10.3390/biom13010069openalex-snapshot

Metabolic Maturation Exaggerates Abnormal Calcium Handling in a Lamp2 Knockout Human Pluripotent Stem Cell-Derived Cardiomyocyte Model of Danon Disease

inferred← citeshttps://doi.org/10.3390/biomedicines11113039openalex-snapshot

Levamisole Modulation of Podocytes’ Actin Cytoskeleton in Nephrotic Syndrome

inferred← citeshttps://doi.org/10.3390/cancers12092515openalex-snapshot

mTOR-Dependent Role of Sestrin2 in Regulating Tumor Progression of Human Endometrial Cancer

inferred← citeshttps://doi.org/10.3390/cancers17091578openalex-snapshot

Sestrins in Carcinogenesis—The Firefighters That Sometimes Stoke the Fire

inferred← citeshttps://doi.org/10.3390/cells10113149openalex-snapshot

Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms

inferred← citeshttps://doi.org/10.3390/cells11152339openalex-snapshot

MiR-23b Promotes Porcine Preadipocyte Differentiation via SESN3 and ACSL4

inferred← citeshttps://doi.org/10.3390/cells15070651openalex-snapshot

Sestrins as Biomarkers of Cellular Stress and Human Disease

inferred← citeshttps://doi.org/10.3390/cells8091105openalex-snapshot

Cellular Stress Responses in Radiotherapy

inferred← citeshttps://doi.org/10.3390/cells9112439openalex-snapshot

Metformin: Metabolic Rewiring Faces Tumor Heterogeneity

inferred← citeshttps://doi.org/10.3390/healthcare8040378openalex-snapshot

Exercise-Induced Myokines can Explain the Importance of Physical Activity in the Elderly: An Overview

inferred← citeshttps://doi.org/10.3390/ijerph19031079openalex-snapshot

Serum Sestrin-1 Concentration Is Higher in Frail than Non-Frail Older People Living in Nursing Homes

inferred← citeshttps://doi.org/10.3390/ijms161125963openalex-snapshot

Roles of Sestrin2 and Ribosomal Protein S6 in Transient Global Ischemia-Induced Hippocampal Neuronal Injury

inferred← citeshttps://doi.org/10.3390/ijms18030545openalex-snapshot

More Insight into BDNF against Neurodegeneration: Anti-Apoptosis, Anti-Oxidation, and Suppression of Autophagy

inferred← citeshttps://doi.org/10.3390/ijms26115174openalex-snapshot

Potential Role of SESN3 in Linking Heart Failure with Preserved Ejection Fraction and Chronic Obstructive Pulmonary Disease via Autophagy Dysregulation

inferred← citeshttps://doi.org/10.3390/ijms26146588openalex-snapshot

The Molecular Interplay Between p53-Mediated Ferroptosis and Non-Coding RNAs in Cancer

inferred← citeshttps://doi.org/10.3390/jcm8071001openalex-snapshot

Emerging Roles of Sestrins in Neurodegenerative Diseases: Counteracting Oxidative Stress and Beyond

inferred← citeshttps://doi.org/10.3390/jpm10030109openalex-snapshot

Sestrin2 Expression Has Regulatory Properties and Prognostic Value in Lung Cancer

inferred← citeshttps://doi.org/10.3390/toxins13020167openalex-snapshot

Transcriptome Analysis of Caco-2 Cells upon the Exposure of Mycotoxin Deoxynivalenol and Its Acetylated Derivatives

inferred← citeshttps://doi.org/10.37349/emed.2023.00124openalex-snapshot

Oxidative stress, inflammation, dysfunctional redox homeostasis and autophagy cause age-associated diseases

inferred← citeshttps://doi.org/10.37349/emed.2023.00129openalex-snapshot

Oxidative stress and inflammation: the root causes of aging

inferred← citeshttps://doi.org/10.3892/ijo.2017.4025openalex-snapshot

Regulation of autophagy and EMT by the interplay between p53 and RAS during cancer progression (Review)

inferred← citeshttps://doi.org/10.52547/nkums.12.4.94openalex-snapshot

The Effect of Moderate Intensity Continuous Training on Skeletal Muscle Autophagy Biomarkers in Elderly Male Rats

inferred← citeshttps://doi.org/10.5604/01.3001.0014.9471openalex-snapshot

Sestryny jako modulatory procesów starzenia i chorób związanych z wiekiem*

inferred← citeshttps://doi.org/10.5772/48554openalex-snapshot

Sestrins Link Tumor Suppressors with the AMPK-TOR Signaling Network

inferred← citeshttps://doi.org/10.5772/50790openalex-snapshot

Antioxidant Role of p53 and of Its Target TP53INP1

inferred← citeshttps://doi.org/10.6084/m9.figshare.14526449openalex-snapshot

Additional file 1 of Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.6084/m9.figshare.14526452openalex-snapshot

Additional file 2 of Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.6084/m9.figshare.14526455openalex-snapshot

Additional file 3 of Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.6084/m9.figshare.14526458openalex-snapshot

Additional file 4 of Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.6084/m9.figshare.14526461openalex-snapshot

Additional file 5 of Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.6084/m9.figshare.14526464openalex-snapshot

Additional file 6 of Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle

inferred← citeshttps://doi.org/10.6084/m9.figshare.19165181openalex-snapshot

Additional file 1 of Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer

inferred← citeshttps://doi.org/10.6084/m9.figshare.19165184openalex-snapshot

Additional file 2 of Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer

inferred← citeshttps://doi.org/10.6084/m9.figshare.19165187openalex-snapshot

Additional file 3 of Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer

inferred← citeshttps://doi.org/10.6084/m9.figshare.19165190openalex-snapshot

Additional file 4 of Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer

inferred← citeshttps://doi.org/10.6084/m9.figshare.19165193openalex-snapshot

Additional file 5 of Sestrin2 reduces cancer stemness via Wnt/β-catenin signaling in colorectal cancer

inferred← citeshttps://doi.org/10.64898/2026.03.13.711672openalex-snapshot

ATM functions as a rheostat of metabolic stress in small-cell lung cancer

inferred← citeshttps://doi.org/10.70675/1f481059zb480z4ff6zb971z48706d3ff583openalex-snapshot

The role of GATOR1 complex, upstream regulator of mTORC1 pathway, in mitochondrial function

inferred← citeshttps://doi.org/10.70675/55ae189az669fz4544z90baz1c170bc934c6openalex-snapshot

Développement de nouveaux tests fonctionnels d'aide à l'interpretation des variants de signification biologique inconnue dans le cadre de prédispositions génétiques au cancer.

inferred← citeshttps://doi.org/10.70675/cf006e65z80d3z43f4za521z25580e174bc9openalex-snapshot

Rôle de la protéine multifonctionnelle E4F1 et de la voie p53 dans l’homéostasie cutanées

inferred← citeshttps://doi.org/10.7150/ijbs.93598openalex-snapshot

Chk2 Modulates Bmi1-Deficiency-Induced Renal Aging and Fibrosis via Oxidative Stress, DNA Damage, and p53/TGFβ1-Induced Epithelial-Mesenchymal Transition

inferred← citeshttps://doi.org/10.7599/hmr.2013.33.2.104openalex-snapshot

Reactive Oxygen Species and Cellular Function Switch

inferred← citeshttps://doi.org/10.7599/hmr.2013.33.2.83openalex-snapshot

Autophagy in Redox Signalling

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